The Gunners, who beat Wolverhampton Wanderers 2-0 at Molineux Stadium on Saturday, head into their clash with the Foxes having won their last four games in all competitions.
However, the north London outfit trail Leicester by nine points with five gameweeks still to go, and were defeated by Brendan Rodgers' men at King Power Stadium in November.
The manager
Mikel Arteta is in his first managerial role after replacing Unai Emery in December 2019, signing a deal until 2023, after leaving his role as Manchester City's assistant manager.
After emerging through FC Barcelona's world-renowned academy system, the Spaniard enjoyed a successful career as a player, often playing as a central midfielder.
His first taste of senior football, meanwhile, came during a year-and-a-half loan spell at Paris Saint-Germain, where he lifted the Intertoto Cup in 2001 before moving to Rangers.
In Scotland, he netted a penalty on the final day of the 2002/03 season as Rangers completed a domestic treble of Scottish Premier League, Scottish Cup and Scottish League Cup honours.
Arteta's second - and final - season north of the border was less successful as Martin O'Neill's Celtic reasserted their dominance over the Scottish game and Rangers finished second.
A year at Real Sociedad was supposed to coincide with a reunion with childhood friend Xabi Alonso, but when he left to join Liverpool, Arteta's new side struggled in La Liga.
That brought about a move to David Moyes' Everton, in the Premier League, where Arteta would help the Toffees regularly challenge for European qualification over six seasons.
In 2011, he moved to the capital to join Arsène Wenger's Arsenal, lifting two FA Cups and Community Shields with the Gunners, before retiring from playing in 2016.
Immediately after, he linked up with Pep Guardiola to become his compatriot's assistant manager at Manchester City, playing a role in the club's two-year dominance over English football.
Despite missing out on the title in 2016/17 to Chelsea, Man City earned successive Premier League triumphs the following two years, sealing 100 and 98 points on each occasion.
The 2017/18 title success coincided with a League Cup win, while the following campaign ended in a domestic treble, with Guardiola's men defeating Watford 6-0 in the FA Cup Final at Wembley.
Earlier this term, meanwhile, Arteta's talent as a coach prompted Arsenal to offer him his first managerial post and he has so far enjoyed a 57.14 per cent win rate in charge of the Gunners.
The squad
In an attempt to return to UEFA Champions League contention, Arsenal underwent a considerable recruitment drive over the summer under previous manager Unai Emery.
In came Lille's Nicolas Pépé for a reported £72M, William Saliba from Saint-Étienne for £27M, Celtic's Kieran Tierney for £25M and £7M-rated defender David Luiz from Chelsea.
Leaving, meanwhile, were Petr Čech (retired), Alex Iwobi (Everton), Laurent Koscielny (Bordeaux), Danny Welbeck (Watford), David Ospina (Napoli) and Carl Jenkinson (Nottingham Forest).
So far this season, forward Pierre-Emerick Aubameyang has scored an impressive 19 Premier League goals, trailing Foxes striker Jamie Vardy by two in the Golden Boot stakes.
Their starting XI in the win over Wolves, meanwhile, was: Martínez, Mustafi, Luiz, Kolasinac, Cédric, Ceballos, Xhaka, Tierney, Saka, Nketiah, Aubameyang.
The trophy cabinet
Arsenal are one of the most successful clubs in English football history, lifting 13 top tier titles, most recently their stunning 'Invincibles' season in 2003/04 under Arsène Wenger.
That was the third Premier League title of Wenger's Arsenal career, a period which also included seven of the Gunners' record 13 FA Cup victories.
However, despite their tremendous achievements in the FA Cup, the Emirates Stadium outfit have only won the League Cup on two occasions - in 1987 and 1993.
The north Londoners have also lifted the Community Shield (formerly the Charity Shield) a remarkable 15 times, while their one European honour was a UEFA Cup Winners' Cup win in 1994.
The stadium
After spending 93 years at Highbury, Arsenal made an emotional move to the breath-taking 60,704-capacity Emirates Stadium in 2006.
Emirates Stadium is the fourth-largest football venue in England after Wembley Stadium, Old Trafford and the newly-opened Tottenham Hotspur Stadium.
With cannons positioned outside the venue, alongside several statues of club legends, the Gunners have made it their home in recent seasons.
It has also staged eight Brazil fixtures since its opening, most recently a 1-0 victory for the five-time world champions over Uruguay in November 2018.
The fixtures
Following successive defeats after the restart against Manchester City and Brighton & Hove Albion, the Gunners have responded admirably, winning four games on the bounce.
A 2-0 victory at Southampton was followed by a 2-1 Emirates FA Cup success at Sheffield United, a 4-0 triumph over Norwich City and Saturday's 2-0 win at Wolves, sealed courtesy of goals from Bukayo Saka and Alexandre Lacazette.
After tackling Leicester on Tuesday, Arsenal have a north London derby away at Tottenham Hotspur on Sunday, before hosting champions Liverpool on Wednesday 15 July.
Then it's an Emirates FA Cup Semi-Final against Manchester City at Wembley, before Aston Villa (A) and Watford (H) in their remaining 2019/20 Premier League fixtures.
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