The Foxes defeated the Blues both at home in the league and in the final of the Emirates FA Cup last season, but fell to a slender reverse at Stamford Bridge, and it is Thomas Tuchel's men who currently lead the top flight standings after 11 matches.
Ahead of Saturday's 12:30pm kick-off on Filbert Way, here's some key things you need to know...
Who's starring on LCFC TV?
Matchday Live, a free broadcast accessible on LCFC.com and @LCFC social media, begins at 11am on Saturday, with presenter Dan Bates in the company of Foxes favourites Gerry Taggart and Tony Cottee – both winners of the League Cup with the Club in 2000.
A 90-minute preview show will get the Foxes faithful ready for kick-off, with news and views, plus pre-match analysis and opinion, before live match commentary from the Filbert Way press box. Matt Elliott, Leicester's match-winner at Wembley 21 years ago, will join James Fielden on the mics.
What's the officiating team?
Paul Tierney will be the man with the whistle on Saturday, assisted by Constantine Hatzidakis and Neil Davies. The fourth official is Craig Pawson. VAR, on the other hand, will be overseen by Jarred Gillett and Harry Lennard.
When does everything happen?
Find all the key matchday timings for Leicester City versus Chelsea...
| Event | Time |
| Matchday Live starts on LCFC TV | 11am |
| Team news confirmed on @LCFC social media | 11:30am |
| BT Sport coverage begins (UK only) | 11:30am |
| Kick-off | 12:30pm |
| Full-time | 2:15pm approx |
| Two-minute goals video on LCFC TV | 5pm |
| Short highlights and clips available on @LCFC social media | 10pm |
| Match of the Day starts on BBC One (UK only) | 10:30pm |
| Full highlights on LCFC TV | 12am (Sunday) |
What happened last time against the Blues?
While the Foxes were beaten 2-1 at Stamford Bridge in May, a weekend earlier, Youri Tielemans struck from distance to write his name into Leicester City folklore as the Club lifted the FA Cup.
In the last home encounter with Chelsea, meanwhile, Wilfred Ndidi and James Maddison found the net in a 2-0 victory, which put City top of the Premier League standings in January.
When can I catch match highlights?
Approximately two hours after full-time, a two-minute highlights package will be available for Digital Members to watch for free on LCFC TV, via the Club's official website (free sign-up).
Before you can watch extended match highlights on LCFC.com, which will be published from midnight (12am) on Sunday, short clips are set to be posted on Leicester City's official social media channels from 10pm on Saturday evening.
All times GMT unless stated otherwise.