The Foxes are unbeaten in 11 matches against the west London outfit, last losing out to them back in 1953. Historically, City have won out on 15 occasions, drawing 11 times, and suffering six defeats.
Ahead of Saturday's latest clash with Brentford, a 3pm GMT kick-off, here are some of the key facts and figures...
Last league encounter
Leicester City 2 Brentford 2
Premier League
King Power Stadium
07/08/2022
Castagne, Dewsbury-Hall / Toney, Dasilva
Last FA Cup encounter
Brentford 1 Leicester City 3
Fourth Round
Gtech Community Stadium
24/01/2021
Sørensen / Ünder, Tielemans (pen), Maddison
Last League Cup encounter
Brentford 0 (2) Leicester City 2 (6)
Second Round Second Leg
Griffin Park
09/10/1984
Ramsey, Smith
The last time
Last Leicester City hat-trick: Arthur Rowley | 19/01/1952 | Second Division | Griffin Park
Last Brentford hat-trick: None
Last Leicester City penalty scored: Youri Tielemans | 24/01/2021 | FA Cup Fourth Round | Gtech Community Stadium
Last Brentford penalty scored: None
All Leicester City post-war penalties: Don Revie, Reg Halton, Arthur Rowley, Youri Tielemans
Brentford post war penalties: None
Last Leicester City own goal conceded: None
Last Brentford own goal conceded: Ken Horne | 24/04/1954 | Second Division | Griffin Park
Last Leicester City debutant: Kiernan Dewsbury-Hall | 25/01/2020, FA Cup Fourth Round | Griffin Park
Last Brentford debutant: Ben Mee, Keane Lewis-Potter | 07/08/2022 | Premier League | King Power Stadium
All Leicester City post war debutants: Arthur E Smith, Norman Plummer, James Johnston, Tom Paterson, David Lowe, Kiernan Dewsbury-Hall.
All Brentford post war debutants: Eric Ventom, Jack Chisholm, Ted Gaskell, Kevin Harris, Tony Harper, Jimmy Anders, Jimmy Hill, Ken Horne, Jimmy D'Arcy, Rowan Alexander, Gerry Peyton, Ben Mee, Keane Lewis-Potter.
Last Leicester City player sent off: None
Last Brentford player sent off: Brian Statham | 09/01/1993 | First Division | Griffin Park
Last Brentford to Leicester City transfer: George Dumbrell | May 1930 | £1,750
Last Leicester City to Brentford transfer: Callum Elder | July 2016 | Loan
Other club connections: Nicky Adams, DJ Campbell, Steve Claridge, Carl Cort, Andy Feeley, Ben Hamer, Jimmy Holmes, Pat Kruse, Jamie Lawrence, Junior Lewis, Dave McCulloch, Liam Moore, Peter McKennon, Eric Odhiambo, Jerry Roberts, Simon Royce, Jeff Schlupp, Tony Sealy, Dean Smith and Tommy Wright.
Leicester City leading goalscorer vs. Brentford: Arthur Rowley | 7 goals
Brentford leading goalscorer vs. Leicester City: Billy Dare | 4 goals