The Foxes have so far defeated Gillingham and Walsall to reach the fifth round of the competition - which they won in 2021.
Ahead of the draw, which is set to take place at around 7pm GMT on Monday, here are the ball numbers:
1. Tottenham Hotspur
2. Southampton
3. Wrexham or Sheffield United
4. Ipswich Town or Burnley
5. Manchester United
6. Grimsby Town
7. Derby County or West Ham United
8. Stoke City
9. Blackburn Rovers or Birmingham City
10. Leicester City
11. Sheffield Wednesday or Fleetwood Town
12. Manchester City
13. Bristol City
14. Brighton & Hove Albion
15. Fulham or Sunderland
16. Leeds United
Stay tuned to @LCFC on social media to find out who City will face next.