Ahead of the draw, which could see the Foxes come up against any of 26 sides in the northern section, LCFC.com has everything you need to know in one place...
When does the draw take place?
The Stadium of Light is the venue of the draw, before Sky Bet League 1 side Sunderland face Championship outfit Sheffield Wednesday. The draw will start from 7pm BST.
How does it work?
While the draw is not seeded, it is nonetheless regionalised into a north and south section. City are in the north section.
How can I follow it?
Live updates of the draw will be provided on Leicester City's official Twitter page, while full information will be posted on LCFC.com shortly after.
When will the ties take place?
The Second Round fixtures are scheduled to occur on 28-30 August, falling between City's Premier League games against Southampton (A) and Liverpool (H).
What are the ball numbers?
NORTH
1. Aston Villa
2. Blackburn Rovers
3. Blackpool
4. Burton Albion
5. Derby County
6. Doncaster Rovers
7. Everton
8. Fleetwood Town
9. Huddersfield Town
10. Hull City
11. Leeds United
12. Leicester City
13. Lincoln City
14. Macclesfield Town
15. Mansfield Town
16. Middlesbrough
17. Newcastle United
18. Nottingham Forest
19. Preston North End
20. Rochdale
21. Rotherham United
22. Stoke City
23. Walsall
24. West Bromwich Albion
25. Wolverhampton Wanderers
26. Sunderland/Sheffield Wednesday
SOUTH
1. AFC Bournemouth
2. AFC Wimbledon
3. Brentford
4. Brighton & Hove Albion
5. Bristol Rovers
6. Cardiff City
7. Cheltenham Town
8. Crystal Palace
9. Exeter City
10. Forest Green Rovers
11. Fulham
12. Millwall
13. Milton Keynes Dons
14. Newport County
15. Norwich City
16. Oxford United
17. Plymouth Argyle
18. Queens Park Rangers
19. Reading
20. Southampton
21. Swansea City
22. Watford
23. West Ham United
24. Wycombe Wanderers